Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | TACR2 | P21452 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855841 | 0.97 | DRD2 (0.43) | DRD2DRD4DRD3HSD17B10TSHR | |
| SCHEMBL9855966 | 0.96 | TSHR (0.45) | DRD2DRD4DRD3HSD17B10TSHR | |
| SCHEMBL9856013 | 0.96 | DRD2 (0.42) | DRD2DRD4DRD3HSD17B10TSHR | |
| SCHEMBL9855283 | 0.96 | DRD2 (0.42) | DRD2DRD4DRD3HSD17B10TSHR | |
| SCHEMBL9855610 | 0.96 | DRD2 (0.42) | DRD2DRD4DRD3HSD17B10TSHR | |
| SCHEMBL9854961 | 0.96 | DRD2 (0.43) | DRD2DRD4DRD3HSD17B10TSHR | |
| SCHEMBL9855149 | 0.95 | DRD2 (0.43) | DRD2DRD4DRD3HSD17B10TSHR | |
| SCHEMBL9855392 | 0.95 | DRD2 (0.43) | DRD2DRD4DRD3HSD17B10TSHR | |
| SCHEMBL10511648 | 0.94 | TSHR (0.43) | DRD2DRD4DRD3HSD17B10TSHR | |
| SCHEMBL9855411 | 0.94 | TSHR (0.45) | DRD2DRD4DRD3HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |