Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10511648 | 0.98 | TSHR (0.43) | TSHRHSD17B10DRD2DRD4DRD3 | |
| SCHEMBL9855411 | 0.98 | TSHR (0.45) | TSHRHSD17B10DRD2DRD4DRD3 | |
| SCHEMBL9854892 | 0.97 | HSD17B10 (0.47) | TSHRHSD17B10DRD2DRD4DRD3 | |
| SCHEMBL9854923 | 0.96 | DRD2 (0.41) | TSHRHSD17B10DRD2DRD4DRD3 | |
| SCHEMBL9854881 | 0.96 | DRD2 (0.43) | TSHRHSD17B10DRD2DRD4DRD3 | |
| SCHEMBL9854831 | 0.95 | TSHR (0.45) | TSHRHSD17B10DRD2DRD4DRD3 | |
| SCHEMBL9855419 | 0.95 | TSHR (0.42) | TSHRHSD17B10DRD2DRD4DRD3 | |
| SCHEMBL9855361 | 0.94 | TSHR (0.44) | TSHRHSD17B10DRD2DRD4DRD3 | |
| SCHEMBL10511907 | 0.94 | DRD2 (0.40) | TSHRHSD17B10DRD2DRD4DRD3 | |
| SCHEMBL9855240 | 0.94 | DRD2 (0.41) | TSHRHSD17B10DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |