Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854923 | 0.96 | DRD2 (0.41) | DRD2DRD4DRD3FFAR1HRH3 | |
| SCHEMBL9855392 | 0.96 | DRD2 (0.43) | DRD2DRD4DRD3FFAR1TSHR | |
| SCHEMBL9854881 | 0.96 | DRD2 (0.43) | DRD2DRD4DRD3FFAR1HRH3 | |
| SCHEMBL9855771 | 0.95 | DRD2 (0.42) | DRD2DRD4DRD3FFAR1TSHR | |
| SCHEMBL9855461 | 0.95 | DRD2 (0.43) | DRD2DRD4DRD3FFAR1HRH3 | |
| SCHEMBL9855273 | 0.95 | DRD2 (0.43) | DRD2DRD4DRD3FFAR1HRH3 | |
| SCHEMBL10511907 | 0.94 | DRD2 (0.40) | DRD2DRD4DRD3FFAR1HRH3 | |
| SCHEMBL9855841 | 0.94 | DRD2 (0.43) | DRD2DRD4DRD3FFAR1TSHR | |
| SCHEMBL9855419 | 0.93 | TSHR (0.42) | DRD2DRD4DRD3FFAR1HRH3 | |
| SCHEMBL9855966 | 0.93 | TSHR (0.45) | DRD2DRD4DRD3FFAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |