Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 5/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10511907 | 0.98 | DRD2 (0.40) | DRD2DRD4DRD3TSHRHSD17B10 | |
| SCHEMBL9855966 | 0.96 | TSHR (0.45) | DRD2DRD4DRD3TSHRHSD17B10 | |
| SCHEMBL9855419 | 0.96 | TSHR (0.42) | DRD2DRD4DRD3TSHRHSD17B10 | |
| SCHEMBL9854961 | 0.96 | DRD2 (0.43) | DRD2DRD4DRD3TSHRHSD17B10 | |
| SCHEMBL9855361 | 0.95 | TSHR (0.44) | DRD2DRD4DRD3TSHRHSD17B10 | |
| SCHEMBL9855240 | 0.95 | DRD2 (0.41) | DRD2DRD4DRD3TSHRHSD17B10 | |
| SCHEMBL10511648 | 0.94 | TSHR (0.43) | DRD2DRD4DRD3TSHRHSD17B10 | |
| SCHEMBL9855411 | 0.94 | TSHR (0.45) | DRD2DRD4DRD3TSHRHSD17B10 | |
| SCHEMBL10511457 | 0.93 | DRD2 (0.40) | DRD2DRD4DRD3TSHRHSD17B10 | |
| SCHEMBL9854892 | 0.93 | HSD17B10 (0.47) | DRD2DRD4DRD3TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068053-A | Liquid crystals for optical apparatus | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-11-26 | — | — | US | disclosed |