Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855471 | 0.82 | HTR7 (0.38) | HTR7CES2CES1POLBGAA | |
| SCHEMBL9855475 | 0.82 | HTR7 (0.38) | HTR7CES2CES1POLBGAA | |
| SCHEMBL9855705 | 0.74 | CES2 (0.44) | HTR7CES2CES1PTPN1NPC1 | |
| SCHEMBL20622547 | 0.73 | HTR7 (0.44) | HTR7CES2CES1PTPN1NPC1 | |
| Propionaldehyde SCHEMBL27524950 | 0.71 | TDP1 (0.53) | HTR7CES2CES1POLBGAA | |
| SCHEMBL9855173 | 0.69 | CES2 (0.40) | HTR7CES2CES1PTPN1NPC1 | |
| SCHEMBL9300976 | 0.69 | CES2 (0.40) | HTR7CES2CES1PTPN1NPC1 | |
| SCHEMBL655375 | 0.69 | HTR7 (0.64) | HTR7CES2CES1PTPN1NPC1 | |
| SCHEMBL9855270 | 0.68 | HTR7 (0.40) | HTR7CES2CES1PTPN1NPC1 | |
| SCHEMBL9855365 | 0.68 | KMT2A (0.41) | HTR7CES2CES1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011947-A | Enzyme inhibitors for cholesterol biosythesis | BRISTOL-MYERS (US) | 1991-04-30 | — | — | US | disclosed |