Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855573 | 0.85 | HMGCR (0.48) | HMGCR | |
| SCHEMBL9855297 | 0.84 | HMGCR (0.39) | HMGCR | |
| SCHEMBL9855294 | 0.84 | HMGCR (0.39) | HMGCR | |
| SCHEMBL9621968 | 0.76 | ALDH1A1 (0.40) | HMGCR | |
| SCHEMBL9622396 | 0.75 | HMGCR (0.46) | HMGCR | |
| SCHEMBL9855223 | 0.75 | HMGCR (0.44) | HMGCR | |
| SCHEMBL9855647 | 0.75 | HMGCR (0.44) | HMGCR | |
| SCHEMBL9855308 | 0.74 | HMGCR (0.43) | HMGCR | |
| SCHEMBL9855703 | 0.74 | HMGCR (0.43) | HMGCR | |
| SCHEMBL9622380 | 0.74 | HMGCR (0.43) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011947-A | Enzyme inhibitors for cholesterol biosythesis | BRISTOL-MYERS (US) | 1991-04-30 | — | — | US | disclosed |