Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855297 | 1.00 | HMGCR (0.39) | HMGCRALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL9855312 | 0.84 | HMGCR (0.47) | HMGCR | |
| SCHEMBL9621968 | 0.77 | ALDH1A1 (0.40) | HMGCRALDH1A1MAPTHTTADRB2 | |
| SCHEMBL9855198 | 0.76 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3 | |
| SCHEMBL9622390 | 0.76 | HMGCR (0.38) | HMGCRMAPTHTTADRB2ADRB1 | |
| SCHEMBL9855712 | 0.75 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3 | |
| SCHEMBL9855396 | 0.75 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3 | |
| SCHEMBL9855706 | 0.75 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3 | |
| SCHEMBL9622023 | 0.75 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3 | |
| SCHEMBL9855395 | 0.75 | HMGCR (0.36) | HMGCRADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011947-A | Enzyme inhibitors for cholesterol biosythesis | BRISTOL-MYERS (US) | 1991-04-30 | — | — | US | disclosed |