Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9855321 | 1.00 | RAB9A (0.41) | RAB9ANPC1ALDH1A1POLBEPHX2 | |
| SCHEMBL9855388 | 0.92 | KMT2A (0.37) | RAB9ANPC1KMT2AHSD11B1 | |
| SCHEMBL9855389 | 0.92 | KMT2A (0.37) | RAB9ANPC1KMT2AHSD11B1 | |
| SCHEMBL9855369 | 0.84 | RAB9A (0.45) | RAB9ANPC1ALDH1A1POLBEPHX2 | |
| SCHEMBL9855365 | 0.76 | KMT2A (0.41) | RAB9ANPC1KMT2AHSD11B1 | |
| SCHEMBL9855210 | 0.69 | CYP1A2 (0.40) | SMN1; SMN2 | |
| SCHEMBL9855216 | 0.69 | CYP1A2 (0.40) | SMN1; SMN2 | |
| SCHEMBL6468965 | 0.69 | SRD5A2 (0.62) | RAB9ANPC1ALDH1A1POLBKDM4E | |
| SCHEMBL9621921 | 0.66 | CYP1A2 (0.37) | NPC1ALDH1A1MEN1KMT2A | |
| SCHEMBL9855471 | 0.66 | HTR7 (0.38) | RAB9ANPC1ALDH1A1POLBHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011947-A | Enzyme inhibitors for cholesterol biosythesis | BRISTOL-MYERS (US) | 1991-04-30 | — | — | US | disclosed |