SCHEMBL9855895

SCHEMBL9855895

COc1ccc(C(C(=O)O)C(C)(C)C)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.51
AKR1C3 P42330 6/20 0.50
AKR1C2 P52895 6/20 0.50
L3MBTL1 Q9Y468 3/20 0.49
ATM Q13315 2/20 0.49
LDHA P00338 1/20 0.49
PTGS2 P35354 3/20 0.47
PTGS1 P23219 3/20 0.47
CYP1A2 P05177 2/20 0.47
TSHR P16473 2/20 0.47
CDC42 P60953 1/20 0.47
RAC1 P63000 1/20 0.47
SLC22A6 Q4U2R8 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
ACP3 P15309 1/20 0.46
ALDH1A1 P00352 2/20 0.45
KMT2A Q03164 1/20 0.44
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22758104 0.85 NPSR1 (0.51) NPSR1AKR1C3AKR1C2L3MBTL1ATM
Hydrochloric Acid SCHEMBL7835532 0.84 NPSR1 (0.47) NPSR1AKR1C3AKR1C2L3MBTL1ATM
SCHEMBL19530053 0.83 PDK1 (0.48) NPSR1AKR1C3AKR1C2L3MBTL1ATM
SCHEMBL19529503 0.83 PDK1 (0.48) NPSR1AKR1C3AKR1C2L3MBTL1ATM
SCHEMBL11452580 0.81 ATM (0.45) AKR1C2L3MBTL1ATMALDH1A1KMT2A
SCHEMBL9785677 0.80 CLK4 (0.45) LDHACYP1A2CA1CA2ALDH1A1
SCHEMBL6809492 0.80 L3MBTL1 (0.47) NPSR1L3MBTL1ATMALDH1A1KMT2A
SCHEMBL1897934 0.79 TSHR (0.50) L3MBTL1ATMTSHRCA1CA2
SCHEMBL4630315 0.79 SRC (0.46) L3MBTL1ATMPTGS1CYP1A2TSHR
SCHEMBL16682784 0.79 SRC (0.46) L3MBTL1ATMPTGS1CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5066675-A Alkynyl substituent, agricultural use SCHERING AKTIENGESELLSCHAFT (DE) 1991-11-19 US disclosed
EP-0261072-B1 SUBSTITUTED PHENYL ACID ESTERS, THEIR PREPARATION AND THEIR USE AS INSECTICIDES AND ACARICIDES SCHERING AKTIENGESELLSCHAFT (DE) 1990-05-16 EP disclosed
EP-0261072-A1 Substituted phenyl acid esters, their preparation and their use as insecticides and acaricides SCHERING AKTIENGESELLSCHAFT (DE) 1988-03-23 EP disclosed