Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 10/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856031 | 0.84 | FFAR2 (0.41) | FFAR2ATML3MBTL1GRIN2DGRIN3B | |
| SCHEMBL11506996 | 0.77 | ADAMTS5 (0.34) | FFAR2LMNA | |
| SCHEMBL77404 | 0.76 | NPC1 (0.40) | ATML3MBTL1NPC1CYP3A4CYP1A2 | |
| SCHEMBL11112490 | 0.73 | FFAR2 (0.50) | FFAR2ATML3MBTL1CYP3A4CYP1A2 | |
| SCHEMBL9855864 | 0.72 | FFAR2 (0.49) | FFAR2ATML3MBTL1CYP3A4CYP1A2 | |
| SCHEMBL22758110 | 0.72 | FFAR2 (0.49) | FFAR2CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2431670 | 0.72 | FFAR2 (0.49) | FFAR2ATML3MBTL1CYP3A4CYP1A2 | |
| SCHEMBL8170317 | 0.72 | FFAR2 (0.49) | FFAR2ATML3MBTL1CYP3A4CYP1A2 | |
| SCHEMBL76267 | 0.71 | L3MBTL1 (0.44) | L3MBTL1BRD4 | |
| SCHEMBL76511 | 0.69 | PPARG (0.37) | L3MBTL1NPC1CYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066675-A | Alkynyl substituent, agricultural use | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-11-19 | — | — | US | disclosed |
| EP-0261072-A1 | Substituted phenyl acid esters, their preparation and their use as insecticides and acaricides | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-03-23 | — | — | EP | disclosed |