Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29804911 | 0.81 | ALOX5 (0.46) | HDAC11MTNR1AMTNR1BALDH1A1SMN1; SMN2 | |
| SCHEMBL749535 | 0.81 | ALOX5 (0.46) | HDAC11MTNR1AMTNR1BALDH1A1SMN1; SMN2 | |
| SCHEMBL22607785 | 0.80 | PARP1 (0.45) | HDAC11ALDH1A1MAPTHSD17B10KEAP1 | |
| SCHEMBL30517094 | 0.79 | ALOX5 (0.51) | ADRA1DADRA1AADRA1BCTNNB1WNT3A | |
| SCHEMBL984368 | 0.79 | ALOX5 (0.51) | ADRA1DADRA1AADRA1BCTNNB1WNT3A | |
| SCHEMBL9119474 | 0.77 | ALDH1A1 (0.44) | GAAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7940212 | 0.76 | TSHR (0.49) | ADRA1DADRA1AADRA1BGAAALDH1A1 | |
| SCHEMBL15621991 | 0.74 | POLB (0.49) | HDAC8HDAC6CTNNB1WNT3AGAA | |
| SCHEMBL27602562 | 0.74 | PARP1 (0.39) | ALDH1A1MAPT | |
| SCHEMBL13347539 | 0.73 | MAPT (0.38) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266849-B1 | PROCESS FOR INTRODUCING A THIOCARBOXYLIC ESTER GROUP AT THE ORTHO-POSITION OF PHENOLS OR PHENYLAMINES | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4857645-A | Process for introducing a thiocarboxylic ester group at the orthoposition of phenols or phenylamines | SHIONOGI & CO., LTD. (JP) | 1989-08-15 | — | — | US | disclosed |
| EP-0266849-A1 | Process for introducing a thiocarboxylic ester group at the ortho-position of phenols or phenylamines | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |