Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.66 |
| ▸ | PDE4A | P27815 | 3/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 2/20 | 0.43 |
| ▸ | TPO | P07202 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19370607 | 0.80 | PDE4A (0.64) | PNPPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL9032111 | 0.80 | PNP (1.00) | PNPPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL25834247 | 0.80 | PDE4A (0.68) | PNPPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL985620 | 0.80 | ADORA2B (0.63) | PNPPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL3699117 | 0.74 | PDE4A (0.73) | PNPPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL7466316 | 0.73 | ADORA2A (1.00) | PNPPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL5515323 | 0.73 | ADORA2A (0.71) | PNPPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL6267430 | 0.72 | PNP (0.45) | PNPPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30488609 | 0.71 | PDE4A (0.74) | PNPPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL27859109 | 0.71 | PNP (0.79) | PNPPDE4AADORA2APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011005929-A1 | PIPERIDINE DERIVATIVE AND ITS USE FOR THE TREATMENT OF DIABETS AND OBESITY | ARENA PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | WO | claimed |