Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ACACB | O00763 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9274036 | 1.00 | NR1I2 (0.53) | NR1I2ALDH1A1RECQLCYP3A4SMN1; SMN2 | |
| SCHEMBL9269142 | 0.86 | NR1I2 (0.50) | NR1I2ALDH1A1RECQLCYP3A4SMN1; SMN2 | |
| SCHEMBL13328217 | 0.85 | LTA4H (0.50) | CYP3A4 | |
| SCHEMBL9271517 | 0.84 | NR1I2 (0.47) | NR1I2ALDH1A1RECQLCYP3A4SMN1; SMN2 | |
| SCHEMBL13328221 | 0.84 | CYP2D6 (0.56) | CYP3A4SMN1; SMN2CYP19A1 | |
| SCHEMBL9267575 | 0.83 | NR1I2 (0.55) | NR1I2ALDH1A1RECQLCYP3A4SMN1; SMN2 | |
| SCHEMBL9267569 | 0.83 | NR1I2 (0.47) | NR1I2ALDH1A1RECQLCYP3A4SMN1; SMN2 | |
| SCHEMBL9270183 | 0.82 | ALDH1A1 (0.54) | NR1I2ALDH1A1RECQLCYP3A4SMN1; SMN2 | |
| SCHEMBL11776919 | 0.82 | ALDH1A1 (0.54) | NR1I2ALDH1A1RECQLCYP3A4SMN1; SMN2 | |
| SCHEMBL122883 | 0.82 | ACACB (0.45) | ACACBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |