SCHEMBL122883

SCHEMBL122883

CCC(C)Oc1ccc(OC(C)CC)cc1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACACB O00763 3/20 0.45
MAPT P10636 1/20 0.44
MTNR1A P48039 2/20 0.41
MTNR1B P49286 2/20 0.41
LTA4H P09960 1/20 0.41
NQO1 P15559 1/20 0.39
GPBAR1 Q8TDU6 1/20 0.38
CYSLTR1 Q9Y271 1/20 0.38
ALDH1A3 P47895 1/20 0.38
MCHR1 Q99705 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.37
SIGMAR1 Q99720 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12521736 0.93 ALDH1A3 (0.48) ACACBMAPTALDH1A3MCHR1POLB
SCHEMBL18754954 0.91 MTNR1A (0.53) MTNR1AMTNR1B
SCHEMBL9888683 0.91 MTNR1A (0.53) MTNR1AMTNR1B
SCHEMBL13064360 0.91 ACHE (0.42) ACACBMAPTMTNR1AMTNR1BKMT2A
SCHEMBL8263616 0.91 ACHE (0.42) ACACBMAPTMTNR1AMTNR1BKMT2A
SCHEMBL13657979 0.89 KMT2A (0.42) ACACBMAPTKMT2A
SCHEMBL9856260 0.89 ACACB (0.40) ACACBMAPTMTNR1AMTNR1BLTA4H
SCHEMBL9856089 0.89 ACACB (0.40) ACACBMAPTMTNR1AMTNR1BLTA4H
SCHEMBL2091722 0.89 ACACB (0.40) ACACBMAPTMTNR1AMTNR1BLTA4H
SCHEMBL12874848 0.89 KMT2A (0.42) ACACBMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2132 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2084226-B1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2013-02-27 EP claimed
US-8114952-B2 Polycarbonate-polyester blends, methods of manufacture, and articles thereof SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-02-14 US claimed
US-8106126-B2 Polycarbonate-polyester blends, methods of manufacture, and articles thereof SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-01-31 US claimed
EP-2288661-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC Innovative Plastics IP B.V. (NL) 2011-03-02 EP claimed
EP-2285903-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC Innovative Plastics IP B.V. (NL) 2011-02-23 EP claimed
US-7686997-B2 Comprising a combination of 10 to 80 weight percent of a polyester, 5 to 50 weight percent of a polycarbonate, and 10 to 90 weight percent of a polyester-polycarbonate copolymer; transparent polyester-polycarbonate blends with improved weatherability and/or chemical resistance. SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-03-30 US claimed
US-7655737-B2 Blend of polycarbonate comprising 10-90 mole percent acrylate units and polyester; improved toughness, impact strength; improvements retained after heat aging or at low temperatures, and obtained without having detrimental effect on other desirable properties such as transparency SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-02-02 US claimed
WO-2009140611-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-11-19 WO claimed
US-20090286062-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-11-19 US claimed
WO-2009140610-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-11-19 WO claimed
US-20090286921-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-11-19 US claimed
EP-2084226-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM Sabic Innovative Plastics IP B.V. (NL) 2009-08-05 EP claimed
EP-2081992-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND METHODS OF USE Sabic Innovative Plastics IP B.V. (NL) 2009-07-29 EP claimed
WO-2008063722-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-05-29 WO claimed
US-20080119618-A1 THERMOPLASTIC COMPOSITION, METHOD OF MANUFACTURE THEREOF, AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-05-22 US claimed
WO-2008060726-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND METHODS OF USE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-05-22 WO claimed
US-20080119617-A1 POLYCARBONATE-POLYESTER BLENDS, METHODS OF MANUFACTURE, AND METHODS OF USE GENERAL ELECTRIC COMPANY (US) 2008-05-22 US claimed
US-20260146128-A1 POLYCARBONATE COMPOSITION, METHOD FOR THE MANUFACTURE THEREOF, AND ARTICLES COMPRISING THE POLYCARBONATE COMPOSITION SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2026-05-28 US disclosed
US-4408064-A CATALYTIC SULFIDING OF A VINYL SILANE DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1983-10-04 US disclosed
US-4384132-A REINFORCEMENT ADDITIVES FOR CROSSLINKABEL RUBBERS DEGUSSA AKTIENGESELLSCHAFT (DE) 1983-05-17 US disclosed