Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 3/20 | 0.63 |
| ▸ | P2RY2 | P41231 | 10/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | P2RY4 | P51582 | 6/20 | 0.48 |
| ▸ | P2RY6 | Q15077 | 6/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1739891 | 0.89 | POLG (0.48) | POLGP2RY2POLBP2RY4P2RY6 | |
| SCHEMBL1740952 | 0.82 | POLG (0.64) | POLGP2RY2P2RY4P2RY6 | |
| SCHEMBL9856521 | 0.82 | POLG (0.50) | POLGP2RY2POLBP2RY4P2RY6 | |
| SCHEMBL29158219 | 0.79 | P2RY2 (0.69) | POLGP2RY2P2RY4P2RY6 | |
| SCHEMBL29158221 | 0.79 | P2RY2 (0.69) | POLGP2RY2P2RY4P2RY6 | |
| SCHEMBL8644096 | 0.79 | LMNA (0.45) | POLGP2RY2POLB | |
| Cystetine Triphosphate SCHEMBL15810768 | 0.79 | P2RY2 (0.80) | P2RY2P2RY4P2RY6 | |
| Cystetine Triphosphate SCHEMBL315351 | 0.79 | P2RY2 (0.80) | P2RY2P2RY4P2RY6 | |
| Ddctp SCHEMBL16807754 | 0.79 | POLG (0.70) | POLGP2RY2POLBP2RY4P2RY6 | |
| Cystetine Triphosphate SCHEMBL21311175 | 0.79 | P2RY2 (0.80) | P2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409227-A2 | Pyrimidine nucleosides, their preparation and pharmaceutical preparations | MATTHES, Eckart, Dr. (DE) | 1991-01-23 | — | — | EP | disclosed |