Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 2/20 | 0.50 |
| ▸ | P2RY2 | P41231 | 10/20 | 0.45 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | POLD1 | P28340 | 1/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1740952 | 0.88 | POLG (0.64) | POLGP2RY2P2RY4P2RY6ENPP1 | |
| SCHEMBL9856523 | 0.82 | POLG (0.63) | POLGP2RY2P2RY4POLBP2RY6 | |
| Stavudine Triphosphate SCHEMBL987898 | 0.81 | POLB (0.60) | P2RY2POLBPOLA1POLD1P2RY6 | |
| Stavudine Triphosphate SCHEMBL26731736 | 0.81 | POLB (0.60) | P2RY2POLBPOLA1POLD1P2RY6 | |
| SCHEMBL9856279 | 0.80 | POLG (0.57) | POLGP2RY2P2RY4POLBPOLA1 | |
| SCHEMBL13199316 | 0.80 | POLG (0.57) | POLGP2RY2P2RY4POLBPOLA1 | |
| SCHEMBL9856583 | 0.80 | POLG (0.56) | POLGP2RY2P2RY4POLBPOLA1 | |
| SCHEMBL624932 | 0.80 | P2RY2 (0.68) | P2RY2P2RY4P2RY6ENPP1P2RY1 | |
| SCHEMBL16805401 | 0.80 | P2RY2 (0.68) | P2RY2P2RY4P2RY6ENPP1P2RY1 | |
| SCHEMBL667969 | 0.80 | P2RY2 (0.68) | P2RY2P2RY4P2RY6ENPP1P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409227-A2 | Pyrimidine nucleosides, their preparation and pharmaceutical preparations | MATTHES, Eckart, Dr. (DE) | 1991-01-23 | — | — | EP | disclosed |