Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856365 | 0.82 | L3MBTL1 (0.50) | NPC1L3MBTL1MAPTMAPK1USP2 | |
| SCHEMBL10795232 | 0.82 | L3MBTL1 (0.50) | NPC1L3MBTL1MAPTMAPK1USP2 | |
| SCHEMBL11886540 | 0.81 | NPC1 (0.65) | NPC1L3MBTL1MAPTMAPK1HSD17B10 | |
| SCHEMBL11439814 | 0.80 | NPC1 (0.65) | NPC1L3MBTL1MAPTMAPK1USP2 | |
| SCHEMBL9856035 | 0.79 | L3MBTL1 (0.59) | NPC1L3MBTL1MAPTMAPK1USP2 | |
| SCHEMBL11305599 | 0.79 | L3MBTL1 (0.60) | NPC1L3MBTL1MAPTMAPK1USP2 | |
| SCHEMBL11320117 | 0.79 | L3MBTL1 (0.53) | NPC1L3MBTL1MAPTMAPK1USP2 | |
| SCHEMBL14903550 | 0.79 | TSHR (0.57) | L3MBTL1TSHRSMN1; SMN2KMT2AHPGD | |
| SCHEMBL14903554 | 0.79 | PARP10 (0.58) | NPC1L3MBTL1HSD17B10SMN1; SMN2KMT2A | |
| SCHEMBL9856511 | 0.79 | L3MBTL1 (0.47) | NPC1L3MBTL1MAPTMAPK1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |