Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | NEU2 | Q9Y3R4 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.38 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856549 | 0.86 | MAN1B1 (0.44) | MAN1B1HTR2CNEU2CXCR4HTR2A | |
| SCHEMBL9856487 | 0.78 | HOGA1 (0.35) | — | |
| SCHEMBL9856460 | 0.78 | PDE4D (0.39) | KMT2A | |
| SCHEMBL9843718 | 0.72 | PDE4D (0.48) | — | |
| SCHEMBL9844144 | 0.72 | PDE4D (0.48) | — | |
| SCHEMBL22992300 | 0.72 | PDE4D (0.48) | — | |
| SCHEMBL9307929 | 0.72 | TYMP (0.41) | MEN1KMT2A | |
| SCHEMBL10773292 | 0.72 | TYMP (0.41) | MEN1KMT2A | |
| SCHEMBL9307935 | 0.72 | TYMP (0.41) | MEN1KMT2A | |
| SCHEMBL25308645 | 0.70 | CXCR4 (0.49) | MAN1B1HTR2CCXCR4HTR2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983726-A | Antitumor agents | SANOFI S.A. (FR) | 1991-01-08 | — | — | US | disclosed |
| US-4902791-A | ANTITUMOR AGENTS | SANOFI S.A. (FR) | 1990-02-20 | — | — | US | disclosed |