SCHEMBL9856628

SCHEMBL9856628

COCC(=O)OC1C=CC(=O)C1

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 6/20 0.44
NFKB2 Q00653 6/20 0.44
RELA Q04206 6/20 0.44
NLRP3 Q96P20 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9857138 0.83 NFKB1 (0.47) NFKB1NFKB2RELANLRP3
SCHEMBL9856529 0.80 NLRP3 (0.48) NFKB1NFKB2RELANLRP3
SCHEMBL9856316 0.79 NFKB1 (0.43) NFKB1NFKB2RELANLRP3
SCHEMBL9856807 0.79 NFKB1 (0.43) NFKB1NFKB2RELANLRP3
SCHEMBL2816078 0.77 NFKB1 (0.49) NFKB1NFKB2RELANLRP3
SCHEMBL2816076 0.77 NFKB1 (0.49) NFKB1NFKB2RELANLRP3
SCHEMBL6439354 0.77 NFKB1 (0.49) NFKB1NFKB2RELANLRP3
SCHEMBL7064509 0.74 NPSR1 (0.32)
SCHEMBL9856885 0.72 NFKB1 (0.46) NFKB1NFKB2RELANLRP3
SCHEMBL9856833 0.72 NFKB1 (0.49) NFKB1NFKB2RELANLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5041620-A Method for producing optically active 2-cyclopenten-4-one-1-ol esters, 2-cyclopenteno-4-one-1-ol ester and complexes thereof with optically active 1,6-diphenyl-2,4-hexadiyne-1,6-diol SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-08-20 US disclosed