Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 5/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.43 |
| ▸ | RELA | Q04206 | 5/20 | 0.43 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857138 | 0.81 | NFKB1 (0.47) | NFKB1NFKB2RELAPRKCANLRP3 | |
| SCHEMBL9856529 | 0.79 | NLRP3 (0.48) | NFKB1NFKB2RELAPRKCANLRP3 | |
| SCHEMBL9856628 | 0.79 | NFKB1 (0.44) | NFKB1NFKB2RELANLRP3 | |
| SCHEMBL9856316 | 0.78 | NFKB1 (0.43) | NFKB1NFKB2RELANLRP3 | |
| SCHEMBL9856885 | 0.78 | NFKB1 (0.46) | NFKB1NFKB2RELANLRP3 | |
| SCHEMBL2816076 | 0.75 | NFKB1 (0.49) | NFKB1NFKB2RELANLRP3 | |
| SCHEMBL2816078 | 0.75 | NFKB1 (0.49) | NFKB1NFKB2RELANLRP3 | |
| SCHEMBL6439354 | 0.75 | NFKB1 (0.49) | NFKB1NFKB2RELANLRP3 | |
| SCHEMBL14586691 | 0.72 | NFKB1 (0.60) | NFKB1NFKB2RELAKDM4EALDH1A1 | |
| SCHEMBL10723516 | 0.71 | NFKB1 (0.43) | NFKB1NFKB2RELANLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041620-A | Method for producing optically active 2-cyclopenten-4-one-1-ol esters, 2-cyclopenteno-4-one-1-ol ester and complexes thereof with optically active 1,6-diphenyl-2,4-hexadiyne-1,6-diol | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-08-20 | — | — | US | disclosed |