SCHEMBL9856716

SCHEMBL9856716

CC(C)c1ncc(CO)n1CO

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 3/20 0.44
POLB P06746 2/20 0.37
CYP2C19 P33261 1/20 0.33
HTT P42858 1/20 0.33
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
THRB P10828 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12125554 0.78 MLYCD (0.46) MLYCDPOLBCYP2C19HTTLMNA
SCHEMBL14152307 0.69 POLB (0.37) POLBCYP2C19HTTLMNATHRB
SCHEMBL13060549 0.68 ALDH1A1 (0.40) MLYCDPOLBCYP2C19LMNASMN1; SMN2
SCHEMBL5656943 0.68 POLB (0.36) MLYCDPOLBCYP2C19HTTSMN1; SMN2
SCHEMBL4699743 0.65 MLYCD (0.33) MLYCDSMN1; SMN2
SCHEMBL12740542 0.64 SMN1; SMN2 (0.42) MLYCDHTTLMNASMN1; SMN2
SCHEMBL10234568 0.63 MLYCD (0.40) MLYCDLMNASMN1; SMN2
SCHEMBL17471263 0.63 CFTR (0.34) POLBCYP2C19LMNASMN1; SMN2ALDH1A1
SCHEMBL25028002 0.62 SMN1; SMN2 (0.37) POLBLMNASMN1; SMN2ALDH1A1
SCHEMBL1447305 0.62 HTT (0.38) MLYCDHTTLMNASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0411409-A1 Tert.-butylesters of substituted 3-hydroxyproponoic acid BASF Aktiengesellschaft (DE) 1991-02-06 EP disclosed