Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6375729 | 0.95 | GABRP (0.42) | ALDH1A1ENPEPFFAR4FFAR1GABRP | |
| SCHEMBL28860025 | 0.92 | ALDH1A1 (0.45) | ALDH1A1ENPEPFFAR4FFAR1GABRP | |
| SCHEMBL6375432 | 0.88 | GABRP (0.50) | ALDH1A1ENPEPGABRPGABRDGABRA1 | |
| SCHEMBL28215667 | 0.87 | ALDH1A1 (0.39) | ALDH1A1ENPEPFFAR4FFAR1GABRP | |
| SCHEMBL1846885 | 0.83 | FFAR4 (0.44) | ALDH1A1FFAR4FFAR1AKR1B1PPARG | |
| SCHEMBL10384012 | 0.80 | LAP3 (0.57) | LAP3 | |
| SCHEMBL28215668 | 0.80 | GABRP (0.46) | ALDH1A1ENPEPGABRPGABRDGABRA1 | |
| SCHEMBL19955270 | 0.79 | LAP3 (0.58) | LAP3 | |
| SCHEMBL22223355 | 0.79 | FFAR4 (0.45) | ALDH1A1FFAR4FFAR1PPARGPPARD | |
| SCHEMBL3122516 | 0.78 | LAP3 (0.48) | LAP3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253179-B1 | A-ACYLAMINO AMINOALKYL PHOPHONATE ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E.R. Squibb & Sons, Inc. (US) | 1991-12-04 | — | — | EP | disclosed |
| EP-0253179-A2 | A-acylamino aminoalkyl phophonate angiotensin converting enzyme inhibitors | E.R. Squibb & Sons, Inc. (US) | 1988-01-20 | — | — | EP | disclosed |