Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434491 | 0.85 | AHR (0.42) | TP53S100A4ALDH1A1HPGDTSHR | |
| SCHEMBL6279610 | 0.81 | CYP3A4 (0.47) | TP53S100A4IDO1ALDH1A1RECQL | |
| SCHEMBL10944556 | 0.81 | ELANE (0.36) | TP53CNR2ALDH1A1HPGDTSHR | |
| SCHEMBL4438343 | 0.80 | TP53 (0.41) | PTPN1TP53HTR2BPDE4DS100A4 | |
| SCHEMBL2113995 | 0.79 | CYP2A6 (0.44) | TP53IDO1ALDH1A1HPGDTSHR | |
| SCHEMBL434680 | 0.78 | GPR3 (0.38) | S100A4CYP2A6 | |
| SCHEMBL5329513 | 0.78 | ALDH1A1 (0.44) | ALDH1A1RXFP1RECQLHPGDTSHR | |
| SCHEMBL7046340 | 0.75 | MAPK1 (0.49) | ALDH1A1HPGDTSHRMAPT | |
| SCHEMBL4607250 | 0.74 | S1PR4 (0.36) | TP53HTR2BPDE4DPTPN11IDO1 | |
| SCHEMBL10395356 | 0.74 | ALDH1A1 (0.35) | TP53ALDH1A1RECQLTSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2882722-A1 | QUINOXALINE DERIVATIVES AS GPR6 MODULATORS | Envoy Therapeutics Inc. (US) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014028479-A1 | QUINOXALINE DERIVATIVES AS GPR6 MODULATORS | ENVOY THERAPEUTICS, INC. (US) | 2014-02-20 | — | — | WO | disclosed |
| EP-0458519-A2 | Synthesis of nucleotide and nucleoside derivatives | EFAMOL HOLDINGS PLC (GB) | 1991-11-27 | — | — | EP | disclosed |
| US-4524168-A | AZO DYES | CIBA-GEIGY CORPORATION (US) | 1985-06-18 | — | — | US | disclosed |