Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 7/20 | 0.43 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27542455 | 0.82 | CASP6 (0.45) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL4375599 | 0.80 | ALDH1A1 (0.53) | MAPK1L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL11516745 | 0.78 | MAPK1 (0.69) | MAPK1TSHRPDE7APDE7BL3MBTL1 | |
| SCHEMBL27276018 | 0.76 | MAPT (0.44) | MAPK1TSHRPDE7AL3MBTL1MAPT | |
| SCHEMBL9261807 | 0.76 | ALDH1A1 (0.61) | MAPK1TSHRKIF18APDE7APDE7B | |
| SCHEMBL9856911 | 0.75 | PTPN1 (0.40) | TSHRMAPTHPGDALDH1A1 | |
| SCHEMBL27735807 | 0.74 | MAPK1 (0.59) | MAPK1TSHRKIF18APDE7APDE7B | |
| SCHEMBL9798917 | 0.74 | TDP1 (0.46) | MAPK1TSHRMAPTMEN1KMT2A | |
| SCHEMBL4651024 | 0.73 | MAPK1 (0.53) | MAPK1TSHRKIF18APDE7APDE7B | |
| SCHEMBL25941799 | 0.73 | ALDH1A1 (0.58) | MAPK1TSHRKIF18APDE7APDE7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399412-A1 | PHOTOLABILE ESTERS AND THEIR USES | The Institute of Cancer Research (GB) | 2004-03-24 | — | — | EP | disclosed |
| WO-2003000644-A1 | PHOTOLABILE ESTERS AND THEIR USES | THE INSTITUTE OF CANCER RESEARCH (GB) | 2003-01-03 | — | — | WO | disclosed |
| EP-0074929-A1 | Polycyclic polyazaheterocycles, process for their preparation and pharmaceutical preparations containing them | CIBA-GEIGY AG (CH) | 1983-03-23 | — | — | EP | disclosed |