Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD1 | P21728 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856862 | 0.83 | HTR2A (0.49) | SLC6A2SLC6A4SLC6A3KCNH2DRD2 | |
| SCHEMBL9857006 | 0.79 | HTR2A (0.50) | SLC6A2SLC6A4SLC6A3KCNH2HRH1 | |
| SCHEMBL9856891 | 0.79 | HTR2A (0.53) | SLC6A2SLC6A4SLC6A3KCNH2HRH1 | |
| SCHEMBL9856740 | 0.77 | HTR2A (0.47) | SLC6A2SLC6A4SLC6A3KCNH2HRH1 | |
| SCHEMBL9857086 | 0.76 | HTR2A (0.53) | SLC6A2SLC6A4SLC6A3KCNH2DRD1 | |
| SCHEMBL3058007 | 0.75 | DRD2 (0.55) | DRD2DRD1DRD4DRD5HRH1 | |
| SCHEMBL9857001 | 0.75 | SLC6A4 (0.40) | SLC6A2SLC6A4KDM4ESMN1; SMN2 | |
| SCHEMBL9856826 | 0.75 | TAAR1 (0.53) | SLC6A2SLC6A4SLC6A3KCNH2DRD1 | |
| SCHEMBL9856563 | 0.75 | TAAR1 (0.53) | SLC6A2SLC6A4SLC6A3KCNH2HRH1 | |
| SCHEMBL9856513 | 0.75 | TAAR1 (0.53) | SLC6A2SLC6A4SLC6A3KCNH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |