Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HRH1 | P35367 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856935 | 0.83 | SLC6A2 (0.49) | HTR2AHRH1SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL9857086 | 0.80 | HTR2A (0.53) | HTR2AHRH1SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL9856891 | 0.80 | HTR2A (0.53) | HTR2AHRH1SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL9856897 | 0.79 | SLC6A2 (0.57) | HTR2AHRH1MEN1KMT2AATM | |
| SCHEMBL9856563 | 0.79 | TAAR1 (0.53) | HTR2AHRH1L3MBTL1AOC3SLC6A2 | |
| SCHEMBL9856513 | 0.79 | TAAR1 (0.53) | HTR2AHRH1MEN1KMT2AAOC3 | |
| SCHEMBL9856826 | 0.79 | TAAR1 (0.53) | HTR2AHRH1SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL9857121 | 0.79 | KDM4E (0.42) | HRH1MEN1KMT2AAOC3SLC6A2 | |
| SCHEMBL9802284 | 0.78 | L3MBTL1 (0.51) | MEN1KMT2ACRHBPCRHR2ATM | |
| SCHEMBL9857006 | 0.78 | HTR2A (0.50) | HTR2AHRH1SLC6A2SLC6A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |