Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 4/20 | 0.51 |
| ▸ | HRH1 | P35367 | 4/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856905 | 0.83 | HTR2A (0.41) | TAAR1HTR2AHRH1SLC6A4SLC6A2 | |
| SCHEMBL9856891 | 0.83 | HTR2A (0.53) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL9857086 | 0.83 | HTR2A (0.53) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL9856736 | 0.82 | HTR2A (0.46) | TAAR1HTR2AHRH1SLC6A4SLC6A2 | |
| SCHEMBL9856826 | 0.81 | TAAR1 (0.53) | TAAR1HTR2AHRH1SLC6A4SLC6A2 | |
| SCHEMBL9856563 | 0.81 | TAAR1 (0.53) | TAAR1HTR2AHRH1AOC3SLC6A4 | |
| SCHEMBL9856705 | 0.81 | HTR2A (0.47) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL9857006 | 0.80 | HTR2A (0.50) | TAAR1HTR2AHRH1SLC6A4SLC6A2 | |
| SCHEMBL9857222 | 0.79 | HTR2A (0.49) | HTR2AHRH1SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL9856862 | 0.79 | HTR2A (0.49) | HTR2AHRH1AOC3SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |