Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857006 | 0.77 | HTR2A (0.50) | TAAR1SIGMAR1HTR2AHRH1ADRA2A | |
| SCHEMBL9857080 | 0.77 | HTR2A (0.50) | TAAR1SIGMAR1HTR2AHRH1UBE2N | |
| SCHEMBL9856602 | 0.77 | CYP2D6 (0.45) | TAAR1SIGMAR1HTR2AHRH1 | |
| SCHEMBL6546357 | 0.73 | SIGMAR1 (0.50) | TAAR1SIGMAR1PPARA | |
| SCHEMBL9391605 | 0.73 | SIGMAR1 (0.40) | TAAR1SIGMAR1CYSLTR2CYSLTR1 | |
| SCHEMBL9857107 | 0.72 | TAAR1 (0.38) | TAAR1HTR2AHRH1 | |
| SCHEMBL9856686 | 0.71 | HTR2A (0.37) | TAAR1SIGMAR1HTR2AHRH1KDM4E | |
| SCHEMBL9856649 | 0.71 | HTR2A (0.41) | TAAR1SIGMAR1HTR2AHRH1KDM4E | |
| SCHEMBL9856945 | 0.70 | HTR2A (0.49) | TAAR1SIGMAR1HTR2AHRH1UBE2N | |
| SCHEMBL9856740 | 0.69 | HTR2A (0.47) | TAAR1SIGMAR1HTR2AHRH1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996235-A | Selectively inhibiting the uptake of serotonin and norepinephrine | ELI LILLY AND COMPANY (US) | 1991-02-26 | — | — | US | disclosed |