Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 15/20 | 0.54 |
| ▸ | RARG | P13631 | 14/20 | 0.54 |
| ▸ | RARA | P10276 | 14/20 | 0.54 |
| ▸ | WDR5 | P61964 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 5/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8565216 | 0.84 | WDR5 (0.47) | RARBRARGRARAWDR5RXRA | |
| SCHEMBL27746158 | 0.79 | WDR5 (0.52) | WDR5KDM4E | |
| SCHEMBL30874069 | 0.78 | WDR5 (0.71) | WDR5KDM4E | |
| SCHEMBL8583240 | 0.78 | RARB (0.61) | RARBRARGRARAWDR5KDM4E | |
| SCHEMBL8345712 | 0.76 | RARG (0.55) | RARBRARGRARARXRARXRB | |
| SCHEMBL9856398 | 0.76 | RARB (0.62) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL9317943 | 0.76 | WDR5 (0.51) | RARBRARGRARAWDR5KDM4E | |
| SCHEMBL7744702 | 0.75 | RARB (0.58) | RARBRARGRARAWDR5KDM4E | |
| SCHEMBL8632470 | 0.75 | HIF1A (0.46) | RARBRARGRARARXRACYP26A1 | |
| SCHEMBL2240626 | 0.74 | WDR5 (0.81) | WDR5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415766-A2 | Use of retinoids for reversing glucocorticoid-induced skin atrophy | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-03-06 | — | — | EP | claimed |