Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1151720 | 0.90 | CDC25B (0.56) | CDC25BMAPTTP53MEN1USP2 | |
| SCHEMBL1542903 | 0.90 | CDC25B (0.56) | CDC25BMAPTTP53MEN1USP2 | |
| SCHEMBL917366 | 0.90 | CDC25B (0.56) | CDC25BMAPTTP53MEN1USP2 | |
| SCHEMBL1152737 | 0.77 | MAPT (0.44) | CDC25BMAPTTP53MEN1USP2 | |
| SCHEMBL8444855 | 0.77 | CDC25B (0.45) | CDC25BMAPTTP53MEN1USP2 | |
| SCHEMBL1152792 | 0.76 | MAPT (0.48) | CDC25BMAPTTP53MEN1USP2 | |
| SCHEMBL9856788 | 0.74 | CDC25B (0.45) | CDC25BMAPTTP53MEN1USP2 | |
| SCHEMBL8136452 | 0.74 | MAPT (0.51) | CDC25BMAPTTP53MEN1USP2 | |
| Buparvaquone SCHEMBL8200585 | 0.74 | CDC25B (0.66) | CDC25BMAPTTP53MEN1USP2 | |
| SCHEMBL9856931 | 0.73 | CDC25B (0.46) | CDC25BMAPTTP53MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123239-B1 | IMPROVEMENTS IN OR RELATING TO ANTIPROTOZOAL AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-11 | — | — | EP | disclosed |