Sugi Predict

Sugi Predict / Compounds / SCHEMBL8136452

SCHEMBL8136452

SCHEMBL8136452

CC1CCC(C2=C(O)C(=O)c3ccccc3C2=O)CC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.51
▸ MEN1 O00255 3/20 0.51
▸ KMT2A Q03164 3/20 0.51
▸ TP53 P04637 3/20 0.51
▸ LMNA P02545 2/20 0.51
▸ USP2 O75604 1/20 0.51
▸ CYP1A2 P05177 1/20 0.51
▸ CYP2C9 P11712 1/20 0.51
▸ HPGD P15428 1/20 0.51
▸ TSHR P16473 1/20 0.51
▸ HIF1A Q16665 1/20 0.51
▸ APAF1 O14727 1/20 0.48
▸ TDP2 O95551 1/20 0.48
▸ RAB9A P51151 2/20 0.41
▸ POLB P06746 1/20 0.41
▸ ESR2 Q92731 1/20 0.41
▸ MAOA P21397 1/20 0.40
▸ ALDH1A1 P00352 5/20 0.39
▸ SMN1; SMN2 Q16637 3/20 0.38
▸ NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9857346 0.84 APAF1 (0.54) MAPTMEN1KMT2ATP53LMNA
SCHEMBL1152475 0.83 MAPT (0.51) MAPTMEN1KMT2ATP53LMNA
SCHEMBL9857552 0.83 MAPT (0.62) MAPTMEN1KMT2ATP53LMNA
SCHEMBL8780939 0.83 MAPT (0.46) MAPTMEN1KMT2ATP53LMNA
Parvaquone SCHEMBL916441 0.83 APAF1 (0.52) MAPTMEN1KMT2ATP53LMNA
SCHEMBL11120067 0.83 APAF1 (0.52) MAPTMEN1KMT2ATP53LMNA
SCHEMBL11116588 0.83 APAF1 (0.52) MAPTMEN1KMT2ATP53LMNA
SCHEMBL11121475 0.83 APAF1 (0.52) MAPTMEN1KMT2ATP53LMNA
Parvaquone SCHEMBL31326459 0.83 APAF1 (0.52) MAPTMEN1KMT2ATP53LMNA
SCHEMBL1542903 0.83 CDC25B (0.56) MAPTMEN1KMT2ATP53LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6043286-A COMBATTING WHITE FLY OR LEPIDOPTERA PESTS BTG INTERNATIONAL LIMITED (GB) 2000-03-28 — — US claimed
US-20160287549-A1 NOVEL METHODS FOR TREATING NEURODEGENERATIVE DISEASES GENZYME CORPORATION 2016-10-06 — — US disclosed
US-20160287549-A1 NOVEL METHODS FOR TREATING NEURODEGENERATIVE DISEASES GENZYME CORPORATION 2016-10-06 — — US disclosed
US-6136200-A DOSING WATER FROM WASTE WATER SYSTEM WITHIN AN DETACKFYING AMOUNT OF INORGANIC AND ORGANIC POLYMER ADDUCT SYSTEM COMPRISING CATIONIC POLYMER UNIT, ANIONIC POLYER UNIT, ACRYLAMIDE UNITS AND ALUMINUM SULFATE OCTAHYDRATE POLYMER RESEARCH CORPORATION (US) 2000-10-24 — — US disclosed
US-6043286-A COMBATTING WHITE FLY OR LEPIDOPTERA PESTS BTG INTERNATIONAL LIMITED (GB) 2000-03-28 — — US disclosed
US-5294352-A Polymer alloy WALDMANN JOHN J (US) 1994-03-15 — — US disclosed
US-RE34486-E Compositions of inorganic-organic alloy with highly charged nitrogen content polymers and their manufacture WALDMANN JOHN J 1993-12-21 — — US disclosed
US-4902779-A WASTE WATER TREATMENT MAXICHEM, INC., A CORP. OF NC 1990-02-20 — — US disclosed
US-4891422-A WASTE WATER TREATMENT MAXICHEM, INC. (US) 1990-01-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160287549-A1 NOVEL METHODS FOR TREATING NEURODEGENERATIVE DISEASES DHODH, DLD, HAGH MAPT 110/4885MEN1 4519/4885KMT2A 1965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.