Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | PAM | P19021 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366215 | 0.89 | IDO1 (0.47) | IDO1PAMNPC1MEN1KMT2A | |
| SCHEMBL7366213 | 0.89 | IDO1 (0.47) | IDO1PAMNPC1MEN1KMT2A | |
| SCHEMBL10510400 | 0.83 | PAM (0.58) | IDO1PAMMAOBALDH1A1MMP1 | |
| SCHEMBL9857863 | 0.83 | PAM (0.58) | IDO1PAMMAOBALDH1A1MMP1 | |
| SCHEMBL18444843 | 0.83 | IDO1 (0.46) | IDO1PAMNPC1MEN1KMT2A | |
| SCHEMBL22064200 | 0.81 | NPC1 (0.47) | IDO1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL22063783 | 0.81 | IDO1 (0.45) | IDO1PAMNPC1MEN1KMT2A | |
| SCHEMBL9203671 | 0.81 | NPC1 (0.53) | NPC1MEN1KMT2APOLBMAOB | |
| SCHEMBL9203661 | 0.81 | NPC1 (0.53) | NPC1MEN1KMT2APOLBMAOB | |
| SCHEMBL15315162 | 0.81 | IDO1 (0.47) | IDO1PAMNPC1POLBMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301401-B1 | LEUKOTRIENE ANTAGONISTS, PROCESS FOR THEIR PREPARATION, THEIR USE IN THE TREATMENT OF ILLNESSES | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-27 | — | — | EP | disclosed |
| EP-0301401-A2 | Leukotriene antagonists, process for their preparation, their use in the treatment of illnesses | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-02-01 | — | — | EP | disclosed |