Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366215 | 1.00 | IDO1 (0.47) | IDO1PAMNPC1MEN1KMT2A | |
| SCHEMBL9857423 | 0.89 | IDO1 (0.47) | IDO1PAMNPC1MEN1KMT2A | |
| SCHEMBL22064200 | 0.89 | NPC1 (0.47) | IDO1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL22063783 | 0.86 | IDO1 (0.45) | IDO1PAMNPC1MEN1KMT2A | |
| SCHEMBL18444843 | 0.85 | IDO1 (0.46) | IDO1PAMNPC1MEN1KMT2A | |
| SCHEMBL15315162 | 0.83 | IDO1 (0.47) | IDO1PAMNPC1POLBMMP1 | |
| SCHEMBL10072115 | 0.81 | IDO1 (0.49) | IDO1PAMNPC1MEN1KMT2A | |
| SCHEMBL10510400 | 0.79 | PAM (0.58) | IDO1PAMMAOBMMP1MMP2 | |
| SCHEMBL9857863 | 0.79 | PAM (0.58) | IDO1PAMMAOBMMP1MMP2 | |
| SCHEMBL22064197 | 0.77 | HDAC3 (0.39) | IDO1PAMNPC1POLBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691958-B2 | Enantioselective cross dehydrogenative coupling reactions and compounds synthesized by the reactions | NORTHWESTERN UNIVERSITY (US) | 2023-07-04 | — | — | US | disclosed |
| US-11691958-B2 | Enantioselective cross dehydrogenative coupling reactions and compounds synthesized by the reactions | NORTHWESTERN UNIVERSITY (US) | 2023-07-04 | — | — | US | disclosed |
| US-11174238-B2 | Enantioselective cross dehydrogenative coupling reactions and compounds synthesized by the reactions | NORTHWESTERN UNIVERSITY (US) | 2021-11-16 | — | — | US | disclosed |
| US-20200181106-A1 | ENANTIOSELECTIVE CROSS DEHYDROGENATIVE COUPLING REACTIONS AND COMPOUNDS SYNTHESIZED BY THE REACTIONS | NORTHWESTERN UNIVERSITY (US) | 2020-06-11 | — | — | US | disclosed |
| US-5137889-A | Hypotensive agents; coronary vasodilators; calcium antagonists; antiinflammatory agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-5034395-A | Hypotensive agents, carboxylated dihydropyridines | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691958-B2 | Enantioselective cross dehydrogenative coupling reactions and compounds synthesized by the reactions | DUOX1, DUOX2, ALDH3A1 | IDO1 763/4885PAM 1237/4885NPC1 4835/4885 |
| US-20200181106-A1 | ENANTIOSELECTIVE CROSS DEHYDROGENATIVE COUPLING REACTIONS AND COMPOUNDS SYNTHESIZED BY THE REACTIONS | DUOX1, DUOX2, ALDH3A1 | IDO1 763/4885PAM 1237/4885NPC1 4835/4885 |
| US-11174238-B2 | Enantioselective cross dehydrogenative coupling reactions and compounds synthesized by the reactions | DUOX1, DUOX2, ALDH3A1 | IDO1 763/4885PAM 1237/4885NPC1 4835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.