Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 11/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 11/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461851 | 0.82 | LIPE (0.56) | SIGMAR1HSD17B1HSD17B2LIPELMNA | |
| SCHEMBL25751951 | 0.81 | SIGMAR1 (0.58) | SIGMAR1HSD17B1HSD17B2PARP1LMNA | |
| Hydrochloric Acid SCHEMBL27926140 | 0.80 | SIGMAR1 (0.57) | SIGMAR1HSD17B1HSD17B2PARP1LMNA | |
| SCHEMBL10210873 | 0.77 | BRD4 (0.52) | SIGMAR1HSD17B1HSD17B2LIPELMNA | |
| SCHEMBL27730314 | 0.77 | HSD17B1 (0.50) | SIGMAR1HSD17B1HSD17B2LIPELMNA | |
| SCHEMBL27347182 | 0.76 | HSD17B1 (0.49) | SIGMAR1HSD17B1HSD17B2LIPELMNA | |
| SCHEMBL6632095 | 0.75 | HSD17B1 (0.57) | SIGMAR1HSD17B1HSD17B2PARP1LMNA | |
| SCHEMBL29674755 | 0.75 | HSD17B1 (0.57) | SIGMAR1HSD17B1HSD17B2LMNANR1I2 | |
| SCHEMBL2088201 | 0.75 | HSD17B1 (0.57) | SIGMAR1HSD17B1HSD17B2LMNANR1I2 | |
| SCHEMBL30229852 | 0.75 | HSD17B1 (0.57) | SIGMAR1HSD17B1HSD17B2LMNANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414153-A1 | N-(substituted benzyloxy)imine derivatives, process for the production thereof, use thereof, and method of use thereof | NIHON NOHYAKU CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |