Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684455 | 0.87 | POLB (0.38) | POLBSMN1; SMN2GAAALDH1A1CYP1A2 | |
| SCHEMBL9417135 | 0.76 | GAA (0.62) | GAAALDH1A1CYP1A2 | |
| SCHEMBL9857513 | 0.75 | ALDH1A1 (0.32) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL9858209 | 0.74 | GAA (0.51) | GAAALDH1A1 | |
| SCHEMBL9417242 | 0.73 | POLB (0.41) | POLBSMN1; SMN2GAAALDH1A1CYP1A2 | |
| SCHEMBL14439985 | 0.72 | GAA (0.54) | GAAALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8960392 | 0.69 | GAA (0.46) | GAAALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6274022 | 0.69 | ELANE (0.43) | ALDH1A1 | |
| SCHEMBL15152327 | 0.68 | SMN1; SMN2 (0.48) | POLBSMN1; SMN2GAAALDH1A1CYP1A2 | |
| SCHEMBL9858280 | 0.68 | GAA (0.31) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055458-A | PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | BEECHAM GROUP P.L.C. (GB) | 1991-10-08 | — | — | US | disclosed |
| EP-0353955-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-02-07 | — | — | EP | disclosed |