SCHEMBL764844

SCHEMBL764844

Cc1cc(O)ccc1C(=O)c1ccc(O)cc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.50
HTT P42858 2/20 0.50
HSD17B1 P14061 1/20 0.48
CES2 O00748 1/20 0.48
CA12 O43570 3/20 0.46
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA7 P43166 3/20 0.46
CA9 Q16790 3/20 0.46
CA14 Q9ULX7 3/20 0.46
ALDH1A1 P00352 2/20 0.46
TSHR P16473 1/20 0.46
NPC1 O15118 2/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TP53 P04637 1/20 0.46
RAB9A P51151 1/20 0.45
HSP90AB1 P08238 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13557813 0.92 ALDH1A1 (0.57) SMN1; SMN2HTTCES2CA12CA1
SCHEMBL30355061 0.89 HTT (0.60) SMN1; SMN2HTTHSD17B1CES2ALDH1A1
SCHEMBL1758224 0.89 HTT (0.60) SMN1; SMN2HTTHSD17B1CES2ALDH1A1
SCHEMBL11019202 0.88 MAPK13 (0.48) SMN1; SMN2HTTHSD17B1CES2ALDH1A1
SCHEMBL11017492 0.87 HSD17B1 (0.47) SMN1; SMN2HTTHSD17B1CES2CA12
SCHEMBL10370024 0.86 CES2 (0.60) SMN1; SMN2HTTHSD17B1CES2CA12
SCHEMBL22078956 0.85 KMT2A (0.40) SMN1; SMN2HTTHSD17B1CES2ALDH1A1
SCHEMBL29963348 0.84 MEN1 (0.68) SMN1; SMN2HTTALDH1A1NPC1MAPT
SCHEMBL9857539 0.84 MEN1 (0.68) SMN1; SMN2HTTALDH1A1NPC1MAPT
SCHEMBL39526 0.84 CA12 (0.61) HTTHSD17B1CES2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109337599-A The MULTILAYER COMPOSITE photovoltaic encapsulation glue film and preparation method of a kind of resisting potential induced degradation and application 杭州福斯特应用材料股份有限公司 2019-02-15 CN claimed
CN-108484559-A Functionalized benzopyran compounds and application thereof 凯捷治疗有限公司 2018-09-04 CN disclosed
CN-105980372-B Functionalized benzopyran compounds and uses thereof 凯捷治疗有限公司 2018-05-08 CN disclosed
CN-105980372-A Functionalized benzopyran compounds and uses thereof 诺沃根有限公司 2016-09-28 CN disclosed
EP-1767090-B1 CLATHRATE COMPOUND, METHOD OF CONTROLLING CONCENTRATION OF AQUEOUS SOLUTION OF AGRICULTURAL-CHEMICAL ACTIVE INGREDIENT, AND AGRICULTURAL-CHEMICAL PREPARATION NIPPON SODA CO (JP) 2015-08-12 EP disclosed
EP-2431433-A1 COATING FLUID FOR FORMING ULTRAVIOLET-ABSORBING FILM, AND ULTRAVIOLET-ABSORBING GLASS ARTICLE Asahi Glass Company, Limited (JP) 2012-03-21 EP disclosed
US-7943803-B2 Clathrate compound, method for controlling concentration of aqueous agricultural chemical active ingredient solution, and agricultural chemical formulation NIPPON SODA CO., LTD. (JP) 2011-05-17 US disclosed
US-20100274006-A1 Clathrate compound, method for controlling concentration of aqueous agricultural chemical active ingredient solution, and agricultural chemical formulation NIPPON SODA CO., LTD (JP) 2010-10-28 US disclosed
US-7737309-B2 Clathrate compound, method for controlling concentration of aqueous agricultural chemical active ingredient solution, and agricultural chemical formulation NIPPON SODA CO., LTD. (JP) 2010-06-15 US disclosed
US-20070281929-A1 Clathrate Compound, Method for Controlling Concentration of Aqueous Agricultural Chemical Active Ingredient Solution, and Agricultural Chemical Formulation NIPPON SODA CO., LTD. (JP) 2007-12-06 US disclosed
EP-1767090-A1 CLATHRATE COMPOUND, METHOD OF CONTROLLING CONCENTRATION OF AQUEOUS SOLUTION OF AGRICULTURAL-CHEMICAL ACTIVE INGREDIENT, AND AGRICULTURAL-CHEMICAL PREPARATION NIPPON SODA CO., LTD. (JP) 2007-03-28 EP disclosed
CN-1856461-A Cycloalkylene compounds as estrogen receptor modulators SMITHKLINE BEECHAM CORP (US) 2006-11-01 CN disclosed
WO-2000059501-A1 WATER-SOLUBLE TRIOXANES AS POTENT AND SAFE ANTIMALARIAL AGENTS JOHNS HOPKINS UNIVERSITY (US) 2000-10-12 WO disclosed
EP-0140050-A1 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1985-05-08 EP disclosed
US-4329360-A Benzophenones and their use as fungicides GAF CORPORATION (US) 1982-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100274006-A1 Clathrate compound, method for controlling concentration of aqueous agricultural chemical active ingredient solution, and agricultural chemical formulation STOM, ALB, GANC SMN1; SMN2 4433/4885HTT 70/4885HSD17B1 3498/4885
US-20070281929-A1 Clathrate Compound, Method for Controlling Concentration of Aqueous Agricultural Chemical Active Ingredient Solution, and Agricultural Chemical Formulation CA3, CA2, STOM SMN1; SMN2 4591/4885HTT 389/4885HSD17B1 2569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.