Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657291 | 0.82 | CTRB1 (0.68) | CTRB1GAAMAPTMEN1KMT2A | |
| SCHEMBL9541619 | 0.82 | CTRB1 (0.68) | CTRB1GAAMAPTMEN1KMT2A | |
| SCHEMBL12595245 | 0.74 | PLAU (0.59) | CTRB1GAAMAPTMEN1KMT2A | |
| SCHEMBL21821885 | 0.72 | MEN1 (0.57) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL658941 | 0.72 | CTRB1 (0.56) | CTRB1GAAMAPTMEN1KMT2A | |
| SCHEMBL10017608 | 0.71 | CTRB1 (0.53) | CTRB1GAAMAPTALDH1A1MAP1LC3B | |
| SCHEMBL16535401 | 0.71 | CTRB1 (0.55) | CTRB1GAAMAPTMEN1KMT2A | |
| SCHEMBL16535402 | 0.71 | CTRB1 (0.55) | CTRB1GAAMAPTMEN1KMT2A | |
| SCHEMBL9857137 | 0.71 | SMN1; SMN2 (0.37) | MAPTKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL5858280 | 0.69 | ALDH1A1 (0.48) | CTRB1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5072023-A | Reacting lactone with ester anion to form cyclohexenone ester; oxidizing or dehydrogenating the intermediate | E. R. SQUIBB & SONS, INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0442495-A1 | Process for preparing highly substituted phenyls | E.R. SQUIBB & SONS, INC. (US) | 1991-08-21 | — | — | EP | disclosed |