Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857315 | 0.90 | ALDH1A1 (0.55) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| SCHEMBL9858268 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| SCHEMBL9857938 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| SCHEMBL9857773 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| SCHEMBL9857274 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| SCHEMBL8921982 | 0.74 | ALDH1A1 (0.47) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| SCHEMBL1082558 | 0.71 | GSK3B (0.38) | ALDH1A1HSD17B10KMT2ARAB9AL3MBTL1 | |
| SCHEMBL8923442 | 0.70 | ALDH1A1 (0.83) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| SCHEMBL9858232 | 0.68 | ALDH1A1 (0.57) | ALDH1A1HPGDALOX15HSD17B10MEN1 | |
| SCHEMBL9858074 | 0.67 | ALDH1A1 (0.48) | ALDH1A1HPGDALOX15HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431371-A1 | 3-Aminopyrroles, process for this preparation and their use as medicaments | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-06-12 | — | — | EP | claimed |