Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LIPE | Q05469 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919988 | 0.81 | HPGD (0.42) | CNR1HPGDMAPTRAB9APOLB | |
| SCHEMBL9858064 | 0.77 | ALDH1A1 (0.57) | HPGDMAPTRAB9APOLBALDH1A1 | |
| SCHEMBL9857856 | 0.76 | ALDH1A1 (0.60) | HPGDMAPTRAB9APOLBALDH1A1 | |
| SCHEMBL9858266 | 0.76 | ALDH1A1 (0.48) | HPGDMAPTRAB9APOLBALDH1A1 | |
| SCHEMBL9858082 | 0.75 | ALDH1A1 (0.48) | HPGDMAPTLIPEPOLBALDH1A1 | |
| SCHEMBL8546577 | 0.75 | ALDH1A1 (0.36) | HPGDLIPEPOLBALDH1A1HSD17B10 | |
| SCHEMBL9857274 | 0.75 | ALDH1A1 (0.47) | HPGDMAPTPOLBALDH1A1HSD17B10 | |
| SCHEMBL9858268 | 0.73 | ALDH1A1 (0.56) | HPGDMAPTLIPERAB9APOLB | |
| SCHEMBL9857315 | 0.72 | ALDH1A1 (0.55) | HPGDMAPTALDH1A1HSD17B10ALOX15 | |
| SCHEMBL9133694 | 0.68 | ALOX15 (0.43) | HPGDPOLBALDH1A1HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431371-A1 | 3-Aminopyrroles, process for this preparation and their use as medicaments | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-06-12 | — | — | EP | claimed |