Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 12/20 | 0.63 |
| ▸ | PNP | P00491 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | POLA1 | P09884 | 1/20 | 0.51 |
| ▸ | POLG | P54098 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858344 | 0.94 | HPRT1 (0.58) | HPRT1PNPPOLBPOLA1POLG | |
| SCHEMBL9858327 | 0.88 | HPRT1 (0.58) | HPRT1PNPPOLBPOLA1POLG | |
| SCHEMBL9417159 | 0.84 | HPRT1 (0.63) | HPRT1PNPPOLBPOLA1POLG | |
| SCHEMBL9858347 | 0.82 | FGFR1 (0.47) | HPRT1PNPPOLB | |
| SCHEMBL9857583 | 0.82 | HPRT1 (0.61) | HPRT1PNPPOLBPOLA1POLG | |
| SCHEMBL9857698 | 0.82 | PNP (0.50) | HPRT1PNPPOLBPOLA1POLG | |
| SCHEMBL9858092 | 0.82 | HPRT1 (0.66) | HPRT1PNP | |
| SCHEMBL9576789 | 0.81 | HPRT1 (0.64) | HPRT1PNPPOLB | |
| SCHEMBL9182617 | 0.81 | TK1 (0.57) | HPRT1PNP | |
| SCHEMBL10448178 | 0.80 | HPRT1 (0.51) | HPRT1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055458-A | PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | BEECHAM GROUP P.L.C. (GB) | 1991-10-08 | — | — | US | claimed |
| EP-0353955-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-02-07 | — | — | EP | claimed |
| US-5055458-A | PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | BEECHAM GROUP P.L.C. (GB) | 1991-10-08 | — | — | US | disclosed |
| EP-0353955-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-02-07 | — | — | EP | disclosed |