Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 8/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | AHCY | P23526 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858021 | 0.86 | CDK1 (0.39) | HPRT1FGFR1SLC22A6NT5ECDK1 | |
| SCHEMBL9857605 | 0.85 | FGFR1 (0.57) | HPRT1FGFR1SLC22A6CYP3A4AHCY | |
| SCHEMBL9417147 | 0.83 | CYP3A4 (0.42) | HPRT1FGFR1SLC22A6NT5ECYP3A4 | |
| SCHEMBL9858092 | 0.83 | HPRT1 (0.66) | HPRT1CYP3A4PNP | |
| SCHEMBL9858347 | 0.81 | FGFR1 (0.47) | HPRT1FGFR1SLC22A6NT5ECYP3A4 | |
| SCHEMBL9417176 | 0.79 | FGFR1 (0.51) | HPRT1FGFR1SLC22A6NT5ECYP3A4 | |
| SCHEMBL9858167 | 0.77 | FGFR1 (0.49) | HPRT1FGFR1SLC22A6NT5ECYP3A4 | |
| SCHEMBL172847 | 0.76 | HPRT1 (0.55) | HPRT1FGFR1SLC22A6CYP3A4CDK1 | |
| SCHEMBL29450587 | 0.76 | HPRT1 (0.55) | HPRT1FGFR1SLC22A6CYP3A4CDK1 | |
| SCHEMBL15516660 | 0.76 | HPRT1 (0.55) | HPRT1FGFR1SLC22A6CYP3A4CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055458-A | PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | BEECHAM GROUP P.L.C. (GB) | 1991-10-08 | — | — | US | claimed |
| EP-0353955-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-02-07 | — | — | EP | claimed |
| US-5055458-A | PURINE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | BEECHAM GROUP P.L.C. (GB) | 1991-10-08 | — | — | US | disclosed |
| EP-0353955-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-02-07 | — | — | EP | disclosed |