SCHEMBL765589

SCHEMBL765589

CC(C)Oc1c(Br)cc(Br)cc1Br

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 4/20 0.47
NPSR1 Q6W5P4 2/20 0.47
LMNA P02545 1/20 0.47
HSD17B10 Q99714 1/20 0.39
ALOX15 P16050 4/20 0.38
TDP1 Q9NUW8 2/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
GABRA1 P14867 3/20 0.34
GABRB1 P18505 2/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
HTT P42858 1/20 0.33
POLB P06746 1/20 0.33
GABRA2 P47869 1/20 0.32
GABRB2 P47870 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1537774 0.85 HSD17B10 (0.39) ALOX12NPSR1LMNAHSD17B10ALOX15
SCHEMBL6285002 0.81 HSD17B10 (0.41) ALOX12NPSR1LMNAHSD17B10ALOX15
SCHEMBL14094174 0.81 LMNA (0.36) ALOX12NPSR1LMNACA2CA4
SCHEMBL9858387 0.81 HSD17B10 (0.37) ALOX12NPSR1LMNAHSD17B10ALOX15
SCHEMBL11171954 0.79 HSD17B10 (0.36) ALOX12NPSR1LMNAHSD17B10ALOX15
SCHEMBL8541393 0.79 HSD17B10 (0.67) ALOX12NPSR1LMNAHSD17B10TSHR
SCHEMBL2544650 0.78 LMNA (0.36) ALOX12NPSR1LMNAGABRA1GABRB1
SCHEMBL10781184 0.78 ALOX12 (0.39) ALOX12NPSR1LMNAHSD17B10ALOX15
SCHEMBL8545552 0.78 HSD17B10 (0.47) ALOX12NPSR1LMNAHSD17B10ALOX15
SCHEMBL11691799 0.76 ALDH1A1 (0.41) ALOX12NPSR1LMNAHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1642932-B1 CURING COMPOSITION KANEKA CORP (JP) 2012-03-21 EP disclosed
EP-2072577-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2010-08-04 EP disclosed
EP-2072577-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2009-06-24 EP disclosed
EP-1970408-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-09-17 EP disclosed
EP-1967533-A1 PHOTORADICALLY AND THERMALLY RADICALLY CURABLE COMPOSITION Kaneka Corporation (JP) 2008-09-10 EP disclosed
EP-1288247-B1 CURABLE COMPOSITIONS AND COMPATIBILIZING AGENT KANEKA CORP (JP) 2008-07-16 EP disclosed
EP-1873175-A1 CURABLE COMPOSITION, ADHESIVE COMPOSITION CONTAINING SUCH CURABLE COMPOSITION, AND ADHESIVE Kaneka Corporation (JP) 2008-01-02 EP disclosed