SCHEMBL9858501

SCHEMBL9858501

C=CCC(C(=O)O)c1ccccc1Sc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 4/20 0.55
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47
MMP12 P39900 1/20 0.47
SIRT1 Q96EB6 1/20 0.41
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
CYP2C9 P11712 3/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
BLM P54132 1/20 0.38
LMNA P02545 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
L3MBTL1 Q9Y468 4/20 0.38
ATM Q13315 1/20 0.38
MAPT P10636 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
HTT P42858 2/20 0.37
CYP2D6 P10635 2/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL598579 0.76 CYP2C19 (0.64) CYP2C19KMT2AMEN1ALDH1A1HPGD
SCHEMBL29962195 0.75 CYP2C19 (0.62) CYP2C19KMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL1908317 0.75 CYP2C19 (0.62) CYP2C19KMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL10952808 0.74 CYP2C19 (0.60) CYP2C19KMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL11497859 0.73 CYP2C19 (0.58) CYP2C19CYP2C9ALDH1A1HPGDATM
SCHEMBL8222695 0.72 MMP12 (0.61) CYP2C19MMP2MMP9MMP12SIRT1
SCHEMBL666893 0.72 CYP2C19 (1.00) CYP2C19ALDH1A1LMNASMN1; SMN2L3MBTL1
SCHEMBL1458057 0.72 CYP2C19 (1.00) CYP2C19ALDH1A1LMNASMN1; SMN2L3MBTL1
SCHEMBL1458050 0.72 CYP2C19 (1.00) CYP2C19ALDH1A1LMNASMN1; SMN2L3MBTL1
SCHEMBL317130 0.72 MMP9 (0.59) MMP2MMP9MMP12KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0279162-B1 CARBONIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICALS CONTAINING THEM Roche Diagnostics GmbH (DE) 1991-06-19 EP claimed