SCHEMBL9858830

SCHEMBL9858830

c1ccc2cc3c(CCc4cccc5cc6ccccc6cc45)cccc3cc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 2/20 0.44
GAA P10253 2/20 0.44
AKR1B1 P15121 1/20 0.42
HIF1A Q16665 1/20 0.42
CYP1B1 Q16678 1/20 0.42
HSD17B10 Q99714 1/20 0.42
HTR2A P28223 3/20 0.42
DAO P14920 1/20 0.42
NQO2 P16083 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
CYP1A2 P05177 2/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MTNR1A P48039 3/20 0.39
ERBB2 P04626 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4945775 0.90 AKR1B1 (0.44) ALDH1A1KDM4EGAAAKR1B1MEN1
SCHEMBL31274181 0.87 L3MBTL1 (0.45) ALDH1A1KDM4EGAAAKR1B1HIF1A
SCHEMBL29114644 0.87 HTR2A (0.41) ALDH1A1KDM4EGAAAKR1B1HIF1A
SCHEMBL28005974 0.87 ALDH1A1 (0.39) ALDH1A1KDM4EGAAAKR1B1HIF1A
SCHEMBL3717317 0.87 TAAR1 (0.47) ALDH1A1KDM4EGAAHTR2AMEN1
SCHEMBL1307677 0.87 GPR84 (0.43) ALDH1A1KDM4EGAAAKR1B1HTR2A
SCHEMBL1456304 0.87 ALDH1A1 (0.43) ALDH1A1KDM4EGAAAKR1B1HIF1A
SCHEMBL11881368 0.87 L3MBTL1 (0.45) ALDH1A1KDM4EGAAAKR1B1HIF1A
SCHEMBL304872 0.87 ALDH1A1 (0.39) ALDH1A1KDM4EGAAAKR1B1HIF1A
SCHEMBL30553971 0.87 TAAR1 (0.47) ALDH1A1KDM4EGAAHTR2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5003116-A Haloethylation of aromatic hydrocarbons ETHYL CORPORATION (US) 1991-03-26 US claimed