Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.44 |
| ▸ | RAF1 | P04049 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21776928 | 0.80 | KDR (0.48) | SLC6A3KDRMAPTKMT2AGAA | |
| SCHEMBL9859159 | 0.80 | KMT2A (0.51) | HSD11B1EPHX2RAF1MAPTKMT2A | |
| SCHEMBL9858976 | 0.77 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPT | |
| SCHEMBL3328716 | 0.77 | CCR2 (0.47) | KDRSMN1; SMN2MAPTKMT2AGAA | |
| SCHEMBL20702662 | 0.72 | KDR (0.50) | HSD11B1SLC6A3KDRMAPTKMT2A | |
| SCHEMBL28077707 | 0.71 | CYP2D6 (0.56) | SMN1; SMN2MAPTKMT2AMAPK1 | |
| SCHEMBL20702651 | 0.71 | NPFFR2 (0.50) | HSD11B1EPHX2SLC6A3KDRMAPT | |
| SCHEMBL30298640 | 0.71 | GSK3B (0.54) | HSD11B1SLC6A3KDRMAPTKMT2A | |
| SCHEMBL1726226 | 0.71 | GSK3B (0.54) | HSD11B1SLC6A3KDRMAPTKMT2A | |
| SCHEMBL30991460 | 0.71 | NPFFR2 (0.50) | HSD11B1EPHX2SLC6A3KDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153127-B1 | N-ARYL-3-ARYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDES, PROCESSES FOR THEIR PRODUCTION, INSECTICIDAL COMPOSITIONS CONTAINING THEM AND METHODS FOR COMBATTING INSECTS | ROHM AND HAAS COMPANY (US) | 1991-04-03 | — | — | EP | disclosed |
| US-4863947-A | PESTICIDES, INSECTICIDES | ROHM AND HAAS (US) | 1989-09-05 | — | — | US | disclosed |
| US-4663341-A | Insecticidal n-aryl-3-aryl-4,5-dihydro-1h-pyrazole-1-carboxamides | ROHM AND HAAS COMPANY (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0153127-A2 | N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamides, processes for their production, insecticidal compositions containing them and methods for combatting insects | ROHM AND HAAS COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |