Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.45 |
| ▸ | RAF1 | P04049 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858945 | 0.80 | HSD11B1 (0.45) | KMT2AEPHX2RAF1TSHRHSD11B1 | |
| SCHEMBL19134194 | 0.78 | KMT2A (0.60) | KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL31757108 | 0.74 | KDR (0.68) | KMT2AEPHX2RAF1NPC1RAB9A | |
| SCHEMBL20702662 | 0.74 | KDR (0.50) | KMT2AHSD11B1MAPTALDH1A1MEP1B | |
| SCHEMBL21776928 | 0.74 | KDR (0.48) | KMT2ARAB9APOLBL3MBTL1MAPT | |
| SCHEMBL16082974 | 0.73 | ATF4 (0.61) | KMT2AEPHX2RAF1NPC1RAB9A | |
| SCHEMBL20702651 | 0.73 | NPFFR2 (0.50) | KMT2AEPHX2HSD11B1MAPTALDH1A1 | |
| SCHEMBL30991460 | 0.73 | NPFFR2 (0.50) | KMT2AEPHX2HSD11B1MAPTALDH1A1 | |
| SCHEMBL1726226 | 0.73 | GSK3B (0.54) | KMT2AHSD11B1MAPTALDH1A1MEP1B | |
| SCHEMBL30298640 | 0.73 | GSK3B (0.54) | KMT2AHSD11B1MAPTALDH1A1MEP1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153127-B1 | N-ARYL-3-ARYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDES, PROCESSES FOR THEIR PRODUCTION, INSECTICIDAL COMPOSITIONS CONTAINING THEM AND METHODS FOR COMBATTING INSECTS | ROHM AND HAAS COMPANY (US) | 1991-04-03 | — | — | EP | disclosed |
| US-4863947-A | PESTICIDES, INSECTICIDES | ROHM AND HAAS (US) | 1989-09-05 | — | — | US | disclosed |
| US-4663341-A | Insecticidal n-aryl-3-aryl-4,5-dihydro-1h-pyrazole-1-carboxamides | ROHM AND HAAS COMPANY (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0153127-A2 | N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamides, processes for their production, insecticidal compositions containing them and methods for combatting insects | ROHM AND HAAS COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |