Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9859266 | 0.80 | CYP3A4 (0.32) | CYP3A4ALDH1A1HPGDTDP1 | |
| SCHEMBL9859297 | 0.75 | CYP3A4 (0.42) | CYP3A4 | |
| SCHEMBL11535245 | 0.72 | TDP1 (0.34) | CYP3A4ALDH1A1HPGDTDP1 | |
| SCHEMBL1899849 | 0.69 | CYP3A4 (0.50) | CYP3A4ALDH1A1HPGDTDP1 | |
| SCHEMBL11082116 | 0.69 | TDP1 (0.36) | CYP3A4ALDH1A1HPGDTDP1 | |
| SCHEMBL11473361 | 0.66 | TDP1 (0.36) | CYP3A4ALDH1A1HPGDTDP1 | |
| SCHEMBL9859146 | 0.66 | CYP3A4 (0.42) | CYP3A4ALDH1A1HPGDTDP1 | |
| SCHEMBL11531900 | 0.66 | CYP3A4 (0.42) | CYP3A4ALDH1A1TDP1 | |
| SCHEMBL23361969 | 0.63 | MEN1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL29758224 | 0.63 | MEN1 (0.33) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153127-B1 | N-ARYL-3-ARYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDES, PROCESSES FOR THEIR PRODUCTION, INSECTICIDAL COMPOSITIONS CONTAINING THEM AND METHODS FOR COMBATTING INSECTS | ROHM AND HAAS COMPANY (US) | 1991-04-03 | — | — | EP | disclosed |
| US-4863947-A | PESTICIDES, INSECTICIDES | ROHM AND HAAS (US) | 1989-09-05 | — | — | US | disclosed |
| US-4663341-A | Insecticidal n-aryl-3-aryl-4,5-dihydro-1h-pyrazole-1-carboxamides | ROHM AND HAAS COMPANY (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0153127-A2 | N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamides, processes for their production, insecticidal compositions containing them and methods for combatting insects | ROHM AND HAAS COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |