SCHEMBL9859274

SCHEMBL9859274

CCCCc1nc(Cl)c(C(=O)O)n1Cc1c2ccocc-2c(Br)c1-c1ccccc1N

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 4/20 0.46
AGTR2 P50052 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9309117 0.92 AGTR1 (0.49) AGTR1AGTR2
SCHEMBL9309667 0.91 AGTR1 (0.41) AGTR1AGTR2
SCHEMBL9309331 0.88 AGTR1 (0.44) AGTR1AGTR2
SCHEMBL9310813 0.88 AGTR2 (0.45) AGTR1AGTR2
SCHEMBL9309984 0.88 AGTR1 (0.44) AGTR1AGTR2
SCHEMBL9859850 0.86 AGTR1 (0.34) AGTR1
SCHEMBL9308209 0.86 AGTR1 (0.39) AGTR1AGTR2
SCHEMBL7301218 0.86 AGTR1 (0.44) AGTR1AGTR2
SCHEMBL3473992 0.86 AGTR1 (0.47) AGTR1AGTR2
Water SCHEMBL9311609 0.85 AGTR1 (0.47) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434249-A2 Benzofuran derivatives GLAXO GROUP LIMITED (GB) 1991-06-26 EP disclosed