Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | BPTF | Q12830 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828028 | 0.85 | MEN1 (0.62) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL7116215 | 0.81 | BPTF (0.53) | ALDH1A1MEN1KMT2AKDM4EBPTF | |
| SCHEMBL7118496 | 0.81 | BPTF (0.50) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL8109869 | 0.80 | BPTF (0.56) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL7116211 | 0.80 | BPTF (0.46) | ALDH1A1MEN1KMT2AKDM4EBPTF | |
| SCHEMBL6822746 | 0.79 | MAPK1 (0.56) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL6944075 | 0.79 | LMNA (0.78) | ALDH1A1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL9829552 | 0.78 | BPTF (0.50) | ALDH1A1MEN1KMT2AKDM4EBPTF | |
| SCHEMBL10790468 | 0.78 | KMT2A (0.54) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL3269214 | 0.77 | CA12 (0.75) | LMNABPTFCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302378-A2 | Sulphonylaminoguanidino azines | BAYER AG (DE) | 1989-02-08 | — | — | EP | claimed |
| US-5010100-A | Skeletal muscular disorders, hydertensive agents, cardiovascular disorders | MERCK & CO. INC. (US) | 1991-04-23 | — | — | US | disclosed |
| EP-0322033-A2 | New 2,5-diaryl tetrahydrofurans and analogs thereof as paf antagonists | MERCK & CO. INC. (US) | 1989-06-28 | — | — | EP | disclosed |