Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | GPR35 | Q9HC97 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL213849 | 0.85 | ALDH1A1 (0.62) | ALDH1A1CYP3A4GPR35MEN1KMT2A | |
| SCHEMBL10818750 | 0.85 | ALDH1A1 (0.62) | ALDH1A1CYP3A4GPR35MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10582751 | 0.83 | ALDH1A1 (0.60) | ALDH1A1CYP3A4GPR35MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL11695961 | 0.83 | ALDH1A1 (0.60) | ALDH1A1CYP3A4GPR35MEN1KMT2A | |
| SCHEMBL28683782 | 0.82 | ALDH1A1 (0.72) | ALDH1A1CYP3A4GPR35MEN1KMT2A | |
| SCHEMBL1494433 | 0.82 | GPR35 (0.47) | ALDH1A1CYP3A4GPR35TDP1HPGD | |
| SCHEMBL1282898 | 0.79 | ALDH1A1 (0.68) | ALDH1A1CYP3A4GPR35MEN1KMT2A | |
| SCHEMBL496363 | 0.79 | ALDH1A1 (0.75) | ALDH1A1CYP3A4GPR35MEN1KMT2A | |
| SCHEMBL31264960 | 0.79 | ALDH1A1 (0.75) | ALDH1A1CYP3A4GPR35MEN1KMT2A | |
| SCHEMBL26694938 | 0.78 | ALDH1A1 (0.50) | ALDH1A1CYP3A4GPR35MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402485-A1 | METHOD OF OBTAINING 2-BROMINE-4,6-DINITROCHLOROBENZENE | ANDRIEVSKY, Alexandr Mikhailovich (SU) | 1990-12-19 | — | — | EP | claimed |
| US-20170369470-A1 | Cyclic Compounds and Uses Thereof | Karyopharm Therapeutics Inc. | 2017-12-28 | — | — | US | disclosed |
| US-20170369470-A1 | Cyclic Compounds and Uses Thereof | Karyopharm Therapeutics Inc. | 2017-12-28 | — | — | US | disclosed |
| WO-2016100515-A1 | CYCLIC COMPOUNDS AND USES THEREOF | Karyopharm Therapeutics Inc. (US) | 2016-06-23 | — | — | WO | disclosed |
| EP-0408759-A1 | METHOD OF OBTAINING BROMATED AROMATIC AND HETEROCYCLIC COMBINATIONS CONTAINING ACCEPTOR GROUPS | ANDRIEVSKY, Alexandr Mikhailovich (SU) | 1991-01-23 | — | — | EP | disclosed |
| EP-0402486-A1 | METHOD OF OBTAINING 2-BROMINE-4,6-DINITROANILINE | ANDRIEVSKY, Alexandr Mikhailovich (SU) | 1990-12-19 | — | — | EP | disclosed |
| EP-0402486-A1 | METHOD OF OBTAINING 2-BROMINE-4,6-DINITROANILINE | ANDRIEVSKY, Alexandr Mikhailovich (SU) | 1990-12-19 | — | — | EP | disclosed |
| EP-0402485-A1 | METHOD OF OBTAINING 2-BROMINE-4,6-DINITROCHLOROBENZENE | ANDRIEVSKY, Alexandr Mikhailovich (SU) | 1990-12-19 | — | — | EP | disclosed |
| EP-0402485-A1 | METHOD OF OBTAINING 2-BROMINE-4,6-DINITROCHLOROBENZENE | ANDRIEVSKY, Alexandr Mikhailovich (SU) | 1990-12-19 | — | — | EP | disclosed |
| CN-1044808-A | Process for preparing brominated aromatic and heterocyclic compounds containing acceptor groups | ALEXANDR MIKHAILOVICH ANDRIEVS (SU) | 1990-08-22 | — | — | CN | disclosed |
| CN-1044093-A | Preparation method of 2-bromo-4, 6-dinitrochlorobenzene | ANDRIEVSKY ALEXANDR M (SU) | 1990-07-25 | — | — | CN | disclosed |
| CN-1043933-A | Preparation method of 2-bromo-4, 6-dinitroaniline | ALEXA DR MIKHAILOVICH ANDRIEVS (SU) | 1990-07-18 | — | — | CN | disclosed |
| WO-1990007489-A1 | METHOD OF OBTAINING 2-BROMINE-4,6-DINITROANILINE | ANDRIEVSKY ALEXANDR M (SU) | 1990-07-12 | — | — | WO | disclosed |
| WO-1990007488-A1 | METHOD OF OBTAINING 2-BROMINE-4,6-DINITROCHLOROBENZENE | ANDRIEVSKY ALEXANDR M (SU) | 1990-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170369470-A1 | Cyclic Compounds and Uses Thereof | MALT1, BCL9, BCL6 | ALDH1A1 2172/4885CYP3A4 3179/4885GPR35 2481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.